R&D

Innovation to Beauty and Health

Pipeline

Pipeline

Hugel continues to research the next generation of biopharmaceuticals.

  • STEP 1

    Candidate selection

    Screening and securing candidates fit for disease areas and therapeutic purposes

  • STEP 2

    Nonclinical study

    Obtaining the property or safety data of the test substance using animals

  • STEP 3

    Clinical study

    Confirmation of safety and effectiveness for humans

  • STEP 4

    Approval

    Safety, efficacy, standards and test methods, approval through drug manufacturing and quality control assessment

Pipeline Indication Candidate selection Nonclinical study Clinical phase I Clinical phase II Clinical phase III Approval
Botulax® Blepharospasm
Glabellar frown lines
Post-stroke upperlimb spasticity
Pediatric cerebral palsy patient with dynamic equinus foot deformity
Eye wrinkles
Overactive bladder
Botulinum toxin formulation development Liquid formulation Glabellar frown, lines hyperhidrosis
Micro-needle toxin formulation Hyperhidrosis
RNAi-based scar treatment Intractable hypertrophic scar
The Chaeum Temporary improvement of facial wrinkles
Penis enlargement
Increase in the volume of the central part of the face
Pipeline Indication Candidate selection Nonclinical study Clinical phase I Clinical phase II Clinical phase III Approval
Botulax® Blepharospasm
Glabellar frown lines
Post-stroke upperlimb spasticity
Pediatric cerebral palsy patient with dynamic equinus foot deformity
Eye wrinkles
Overactive bladder
Botulinum toxin formulation development Liquid formulation Glabellar frown, lines hyperhidrosis
Micro-needle toxin formulation Hyperhidrosis
RNAi-based scar treatment Intractable hypertrophic scar
The Chaeum Temporary improvement of facial wrinkles
Penis enlargement
Increase in the volume of the central part of the face